Torres, L. N.1 and Chadwick, L.1, (1)Bell's Brewery, Inc., Galesburg, MI, USA
Technical Session 1: Omics
Sunday, June 04, 2017
10:15–11:30 a.m.
Caloosa Ballroom
Gas chromatography coupled with mass spectrometry (GCMS) is becoming a practical analytical tool for smaller and smaller companies throughout the food and beverage industries. The wealth of information provided by GCMS, coupled with continuous improvements and decreasing costs of instruments, will ensure that more and more (and smaller and smaller!) breweries will adopt this technology. Without question, stable isotope dilution assays (SIDA) are the gold standard for quantitative mass-spectrometric analyses. MetabAromics (MA) is proposed as a complementary approach to SIDA, as a means of maximizing the value of mass chromatograms, in particular for analytes where analytical standards are not available. SIDA provides excellent precision and accuracy for a handful of key target molecules, whereas MA provides information about all detectable analytes. This presentation will detail the process of establishing the MA platform, from collating literature information for over 800 volatile compounds known from hops and/or beer, through optimization of data acquisition and processing parameters. The presentation will also highlight some of the inherent risks of the MA approach.
Lucas Chadwick received a B.A. degree in chemistry from Kalamazoo College in Kalamazoo, MI. He went on to earn his Ph.D. degree from the University of Illinois at Chicago (UIC), where his work at the UIC/NIH Center for Botanical Dietary Supplements Research focused on the pharmacognosy of hops. After a post-doctoral appointment in the Botanical Center, he began employment at Kalsec, Inc., where he worked on natural antioxidants and process development. In 2006, Luke co-founded Wrightwood Technologies and was subsequently awarded a Small Business Innovative Research Grant to automate a preparative chromatographic technique known as countercurrent chromatography. Luke joined Bell’s Brewery, Inc. in 2010 as quality/lab manager and has served as senior scientist at Bell’s since 2015.
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