MATTHEW J. TRASS (1), Phillip Koerner (1), Jeff Layne (1), Sky Countryman (1)
(1) Phenomenex, Torrance, CA
Iso-α-acids, derived from hops, have a significant impact on the
taste of all beers. Therefore, monitoring the iso-α-acids profile and
content during beer production and in the final product is very
important. Using typical methods for analyzing these compounds can
result in run times of 15–20 min or longer with undesirable peak shape.
In conjunction with a quick and easy solid-phase extraction cleanup
method, an improved HPLC method for iso-α-acids in beer is demonstrated
using a Kinetex 2.6-µm core-shell column, resulting in improved peak
shape, quantitation, and dramatically reduced analysis times.
Matthew Trass received a B.S. degree in chemistry from the University
of Otago in Dunedin, New Zealand. He began employment with Phenomenex
in 2006 as an application chemist. With Phenomenex he has developed GC,
SPE, and LC methods, as well as conducted training seminars.
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